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And in blood vessels that are already less flexible or have cholesterol plaques, reintroducing estrogen in the form of hormone replacement therapy can increase the force and speed of blood flow with each heartbeat, sometimes causing a plaque in a vessel to break off and raising the risk of serious problems like heart attack, stroke, or blood clots, says Chervenak

The result is a significant reduction in hunger, a feeling of fullness after smaller meals, and fewer cravings particularly for high-calorie, highly palatable foods

Patient safety and well-being are our top priorities

It reduced pro-inflammatory cytokines (TNF-, IL-6, IL-1), chemokines, adhesion molecules and oxidative stress, while upregulating the expression of neurotrophic factors (neuritin and NGF) [11]

Journal of Diabetes Investigation