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Most people who respond to supplementation notice initial changes around 4 to 8 weeks of consistent daily use, though individual responses vary based on diet, lifestyle and starting levels

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The synergy might arise from the combined action of GHK-Cu in stimulating glycosaminoglycan production, promoting collagen synthesis, and HA's role in reducing collagen degradation by scavenging reactive oxygen species and inhibiting matrix metalloproteinases

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