Both are GHRH analogs that act on the same pituitary receptor
Jacobs, D
The gastrointestinal tolerability profile is an important consideration when initiating therapy and counseling patients about what to expect during treatment

"This is why we felt it was important to make Ozempic, the GLP-1 with the broadest range of FDA-approved indications for adults with type 2 diabetes, more affordable to those without insurance who deserve the real thing." Ozempic is the GLP-1 with the most FDA-approved uses for patients with type 2 diabetes including, improvement of blood sugar, along with diet and exercise, in adults with type 2 diabetes, risk reduction of major cardiovascular events such as heart attack, stroke, or death in adults also with known cardiovascular (CV) disease, lowering the risk of worsening kidney disease, kidney failure (end-stage kidney disease), and death due to CV disease in adults who also have chronic kidney disease.1 Today, millions of people have taken Ozempic2 in the US to help address these chronic conditions, yet there are still some without adequate coverage seeking improved access.
Identification of cystathionine beta-synthase inhibitors using a hydrogen sulfide selective probe