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Striatum D3R D3R expressed on striatal neurons can raise dopamine concentration, decrease -Syn accumulation, enhance secretion of BDNF, ameliorate neuroinflammation, alleviate oxidative stress, and promote neurogenesis in the nigrostriatal pathway
Many investigators benefit from examining a panel of related compounds in parallel, as this approach can reveal differential effects and structure-activity relationships not apparent from single-compound studies
P140 Peptide Leads to Clearance of Autoreactive Lymphocytes and Normalizes Immune Response in Lupus-Prone Mice
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Poor CYP2D6 metabolizers, and those taking medications which inhibit CYP2D6 (such as fluoxetine or quinidine) will need lower doses of atomoxetine
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