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Agents such as liraglutide (3.0 mg daily) and once-weekly semaglutide have been approved for obesity treatment, achieving weight reductions of approximately 515% in many patients Highdose GLP-1RAs significantly reduce body weight by suppressing appetite and calorie intake [234]

Si el paciente ha necesitado MTD para perder peso, probablemente necesitar MTD (o al menos dosis intermedias) para mantenerlo

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