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1.1 Expanded indications and increasing disease prevalence In addition to type 2 diabetes and weight management as key battlegrounds today, GLP-1 therapies have shown clinical promise in treating a wider array of conditions, including Alzheimers disease, cardiovascular risk reduction , MASH (metabolic dysfunction-associated steatohepatitis) and chronic kidney disease (CKD)

Combined with NE requirements, low arterial lactate and high pH appear valuable markers for initiating AVP, reflecting less severe septic shock

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