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Diabetes Care 2013;36:20018

Darenskaya MA, Kolesnikova LI, Kolesnikov SI

Large-scale, prospective trials are needed to confirm its long-term safety and efficacy

Routine consultation with your healthcare provider is appropriate when: Taste changes lead to significant unintentional weight loss beyond treatment goals Nutritional intake becomes severely restricted, raising concerns about deficiencies Taste alterations persist beyond 8-12 weeks without improvement Quality of life is substantially impacted by food aversions or taste disturbances New or worsening symptoms develop, such as persistent metallic taste with other concerning features Your provider can assess whether taste changes represent expected treatment effects or require investigation for alternative causes