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Plasma levels of endogenous and stable isotopelabeled l-carnitine, BB, and TMAO were determined by stable isotope dilution liquid chromatographytandem mass spectrometry (LC-MS/MS) in positive multiple reaction monitoring (MRM) mode as previously described (6) using a Shimadzu 8050 triple quadrupole mass spectrometer with ultra-HPLC interface

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This transformation is usually accompanied by a rise in the production of uncoupling protein 1 (UCP1), a mitochondrial protein that increases energy expenditure and generates heat by uncoupling the respiratory chain

1066-P: Cost-effectiveness of SGLT2i plus GLP-1RAs vs

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