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Nausea and gastrointestinal symptoms peak during weeks 6-8, then improve substantially by week 12

After drug treatment for indicated time, 500 nM final concentration of SYTOX Green Nucleic Acid dye was added into each well, cells were further incubated at 37 C for 15 min, and images of at least three randomly chosen fields were captured by an inverted fluorescence microscope (Olympus, Japan)

The assay based on the reaction of GSH with 5,5-dithio-bis-2-nitrobenzoic acid (DTNB) in the presence of glutathione reductase, was performed according to the protocol 56 and measured with a TECAN plate reader at 412 nm

Store tightly sealed in the original packaging in a cool, dry place, avoiding direct sunlight

Neurotrophic property of geniposide for inducing the neuronal differentiation of PC12 cells