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Molecular biology and pharmacological studies ruled out apoptosis and necroptosis, while increased lipid peroxidation and surface expression of the transferrin receptor implicated ferroptosis as the mechanism of the H 2 O 2 -induced cell death: this was supported by suppression of H 2 O 2 -cytotoxicity by liproxstatin-1, a pharmacological inhibitor of ferroptosis
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Founded 2006
doi: 10.1111/gcb.13969 9
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