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Isaacs says that while most people can safely take a GLP-1, you should avoid it if you have severe gastroparesis (stomach paralysis)

In addition, GLP-1 also increases how full we feel after meals

6 With the increasing trends in type 2 diabetes and obesity, the overall prevalence of MASLD is expected to rise to 55% by 2040, and with it, MASH rates will escalate as well

The slowing of gastric emptying and the associated reduction in appetite mean that many patients on GLP-1 therapy consume smaller portions and may experience changes in food preferences

The retail pharmacies segment contributed the biggest market share of 54% in 2025, driven by the primary dispensing channel for chronic therapy