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small molecule thiol-rich anti-oxidants such as thioredoxin and metallothionein

This occurs through an indirect mechanism by reducing the synthesis and secretion of antiadipogenic cytokines by malignant epithelial cells and fibroblasts

TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor

The coupling of A-GSH targeting ligands resulted in significantly higher BBB penetrations for the 3-PLG-dopa-A-GSH nanocarriers both in the presence of organoids from healthy (3-PLG-dopa-A-GSH P app : 6.52 10 6 cm/s) and PD cells (3-PLG-dopa-A-GSH P app : 6.80 10 6 cm/s) compared to the permeability values of non-targeted formulations

Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways