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And women who are pregnant or breastfeeding need more
Evidence grade Preclinical evidence only Regulatory status No FDA-approved indication and no exact-name ClinicalTrials.gov record located as of July 12, 2026
(as long as the causative factor for B 12 deficiency persists, therapy should be continued) Evidence from animal and human studies shows that B 12 also has neuroprotective and anti-inflammatory properties, 15 and intervention studies in humans have reported beneficial effects of better B 12 status or B 12 therapy in multiple sclerosis, 16 Parkinsons disease, 17 myalgic encephalomyelitis, 18 autism, 19 and (administering very high doses of methylcobalamin) in amyotrophic lateral sclerosis
Its all about placement, and its all about the skill of in the injector
For home use injections, providers often advise not exceeding a cumulative ~300 mg per week unless theres a specific indication
