doi: 10.1016/j.msard.2021.103166 18 BenedictR
Tier 1 protocols may range from $300-600 monthly, Tier 2 from $500-1,200 monthly, and Tier 3 from $800-2,000 monthly depending on complexity
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(1) Omega-3 PUFAs (EPA/DHA) as core antidepressant components Deep-sea fish (e.g., salmon, mackerel) contain 23 g/100 g of EPA and DHA, which target two key pathways of depression: Inhibiting microglial activation: by inhibiting the NF-B/MAPK p38 signaling pathway and activating the neuronal BDNF-PI3K/AKT pathway, the process achieves a balance in microglial M1/M2 polarization and provides neuroprotection against neuroinflammation (313)
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