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The SURMOUNT-MMO trial is examining whether tirzepatide reduces overall morbidity and mortality in adults with obesity but without diabetes

Diabetic retinopathy: Rapid improvements in glycaemic control as may occur with potent glucose-lowering agents have been associated with worsening of diabetic retinopathy in some patients

Diet control, moderate exercise, behavior modification programs, bariatric surgery and prescription drug treatment are the major interventions used to help people lose weight