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Extensive collagen IV or reticulin basement membrane staining supports Schwannian differentiation
Results:May vary from person to person
Heterozygous carriers or minors with one copy of the thalassemia trait gene have no symptoms whereas a child/adult with homozygous thalassemia will present with the disease
M.SavadkarS.WuY.KhanM.et al (2018)
suggests that a key element in this process involves the activation of G-proteins, which are closely associated with the inner surface of the cell membrane and activate downstream pathways leading to the production of secondary messengers such as cyclic adenosine monophosphate (cAMP) and inositol triphosphate (IP3)
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