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These effects of the T allele of APOA1 rs670 may be mediated by changes in apolipoprotein A1 expression (encoded by APOA1 ) or by the inhibitory effects of apolipoprotein A1 on IL-1 production, which may contribute to the initiation and resolution of gout attacks

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Serious reactions include anaphylaxis and angioedema (severe swelling of the face, lips, tongue, or throat)

On-Label vs Off-Label Use and Regulatory Considerations Because BPC-157 is not approved by the FDA for any indication, any human use is off-label or within research settings