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The proposed condensation domain C* (CesA_C2) 8 transfers the hydroxy group of D- O -Leu-D-Ala- S -PCP to the thioester carbon of L- O -Val-L-Val- S -PCP to form an ester bond resulting in the PCP-bound tetradepsipeptide L- O -Val-L-Val-D- O -Leu-D-Ala- S -PCP ( DP4 ) 24 , which is subsequently transferred to the serine hydroxy group of the CesB C-terminal TE domain (Fig

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Comparative effectiveness and use cases Modality selection should weigh indication and urgency of effect, comorbidities and medication burden, standardization and labeling requirements, scalability and access, and patient preference

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