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While LBM loss appears to be less pronounced than FBM loss in many studies, the clinical significance of even modest reductions in skeletal muscle remains uncertain, particularly in older adults or individuals at risk of sarcopenia

In addition to glucose regulation, GLP-1 analogues have additional metabolic action

GLP-1 s also inhibit gastric emptying and induce gastroparesis, which induces satiety and reduces appetite and food intake, therefore limiting weight gain [1]

GLP-1 exerts anti-inflammatory effects by suppressing the NF-B signaling pathway, which leads to a decrease in the production of pro-inflammatory cytokines like TNF- and IL-6, thereby mitigating liver inflammation and fibrosis

Unlike the hormone your body produces, these medications are modified to resist breakdown by DPP-4, allowing them to remain active for much longeroften for days rather than minutes