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The rats were acclimatized in a controlled environment at 22 1 C with a 12/12 h light/dark cycle, with unlimited access to food and water, for two weeks prior to the experiments

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We identified one component that did not involve protein stretching into the membrane

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Studies have shown that the composition and function of the intestinal microbiota are altered in RA patients, with reductions in microbial species such as Faecalibacterium, Flavobacterium, Bifidobacterium, Bacteroides, and Haemophilus and increases in Lactobacillus, Prevotella, and Clostridium [76, 77]