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Normal distribution was tested visually on a histogram of the residuals and differences between group means or medians were assessed using ANOVA and post-hoc analyses using Tukeys post-hoc test

Giant Diverticulum This is the case of a 65-year-old lady with abdominal pain and constipation, this image is found in a colonoscopy, Giant colonic diverticulum is defined by a diverticulum whose diameter is greater than 4 cm

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Compounding is a practice in which a licensed pharmacist, a healthcare professional, and people working under the direct supervision of licensed pharmacists mix, combine, or alter ingredients of the medication in a state-licensed compounding pharmacy

Ethics statement The studies involving human participants were reviewed and approved by CEIM SEVILLE