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Evidence is preliminary, and it is not an FDA-approved treatment for any medical condition

Nasal sprays are less invasive than injections and therefore more suited to regular use

First, sublingual bioavailability consistently exceeds oral bioavailability, often by an order of magnitude

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16 On the other hand, the investigational use of GIPR agonists (GIPRAs) has not yielded similar advantages, partly because of a lack of understanding of GIP dose-response actions