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ClinicalTrials.gov identifier: NCT03456700

It works by mimicking the GLP-1 hormone, which helps control blood sugar levels in the body

Upon oxidation, bilirubin is converted into various forms of bilirubin oxidation metabolites (BOMs), comprising at least seven hydrophilic metabolites that are promptly excreted into urine because of their hydrophilic nature (132)

The tradeoff: more receptor targets mean more potential side effects

GLP-1-Based Strategies for the Treatment of T2DM A GLP-1-based strategy for the treatment of T2DM is indicated in view of the fact that GLP-1R agonists and DPP-IV inhibitors exert a beneficial constellation of physiological effects that include (1) glucose-dependent stimulation of insulin secretion, (2) suppression of glucagon secretion, (3) normalization of blood glucose without an attendant risk of hypoglycemia, (4) slowing of gastric emptying, (5) appetite suppression, and (6) weight loss