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Safety endpoints were analyzed using the safety analysis set of all randomized participants exposed to at least one dose of randomized treatment

In a study by Tromp et al., hyperkalemia was more prevalent among patients with more severe HF, highlighting that these individuals may be more difficult to treat with guideline-directed medical therapy (GDMT) due to heightened risk for treatment-related adverse effects [57]

Insoluble fiber adds bulk to the stool and helps the contents of the digestive tract move more easily, which helps to prevent or treat constipation

Hepatology 2014;60:715735