However, its relative impact on overall intraepithelial cell levels of GSH, or activation of other proinflammatory mediators, is unclear and requires further study
Compared to the former speculation, another study found that adipocytes can secrete specific fatty acids to induce ferroptosis resistance in breast cancer cells, and this process was dependent on the fatty acid synthetase ACSL3, confirming that breast cancer cells co-cultured with peri-tumor adipocytes showed resistance to ferroptosis (82)
GPT & Claude hedge
Vani GT, Mukesh N, Siva Prasad B et al (2010) Role of glutathione S-transferase Mu-1 (GSTM1) polymorphism in oligospermic infertile males
Mukherjee U, Samanta A, Biswas S, Ghosh S, Das S, Banerjee S, et al