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Furthermore, C12 as compared with C10 suppressed appetite and energy intake.56 High fat intake seems to have long-lasting effect on CCK: after a high-fat evening meal, CCK concentrations remained elevated until the following morning.57 Cholecystokinin initiates satiety by acting at cholecystokinin type 1 receptor (CCK1R) located on vagal afferent nerve terminals

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USA 114 , E10418E10427 (2017)