These medications include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)though tirzepatide is technically a dual GIP/GLP-1 receptor agonist, not a GLP-1 RA
Measurable changes in body composition typically appear by weeks 68
Ethics declarations Ethical approval This study is compliant with the principles of the Declaration of Helsinki on research ethics
The eluted protein was concentrated and injected into a Superose 6 10/300 GL size-exclusion column equilibrated with buffer containing 20 mM Tris-Cl (pH 8.0), 150 mM NaCl, and 0.02% DDM
If a vial appears to have lost its vacuum (no audible hiss when the cap is removed) or shows any signs of physical compromise, perform additional quality checks before using the material