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Ipamorelin could thus represent an effective and cheaper alternative to the current options for the treatment of bone loss, such as bisphosphonates, hormonal treatment with PTH or new monoclonal antibodies

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This helps in understanding the downstream effects on cellular proliferation, differentiation, and metabolism

Nausea, vomiting, constipation, and diarrhea are the most common side effects of GLP-1s though some people also experience: headaches increased infections rapid heart rate dizziness indigestion Learn more: Common GLP-1 Side Effects: What to Expect Many GLP-1s are administered by injection once weekly, but there are some exceptions

Nevertheless, some concerns have been raised for the CV safety profile of saxagliptin which led to slightly more hospitalizations for heart failure (HHF) (3.5 vs 2.8% versus placebo