Epigenetic and Transcriptomic Regulation A 2021 study in Communications Biology reported that treatment with the GLP-1s exenatide reversed transcriptomic aging signatures across multiple mouse brain cell populations, including glial and neurovascular cells [7]
What the Research Shows Recent research on semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) has revealed concerning trends about body composition changes: A 2023 analysis of STEP trial data found that approximately 39% of weight lost on semaglutide was lean body mass 1 Research on tirzepatide showed similar patterns, with 30-40% of total weight loss coming from lean tissue 2 Comparative studies indicate GLP-1 users may lose more muscle than people losing weight through diet and exercise alone 3 For context: if you lose 50 pounds on a GLP-1 medication, 15-20 pounds might be muscle mass
Evidence-based stress reduction techniques include mindfulness meditation, yoga, deep breathing exercises, and regular physical activity
When you apply something that speeds up how quickly skin cells renew, all the congestion lurking beneath the surface gets pushed up faster than it would naturally
FAD, Flavin adenine dinucleotide
