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Additionally, non-motor symptoms include gastrointestinal (GI) disorders such as constipation, dysphagia, and delayed gastric emptying [3, 4]

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During the experiment, all animals were subjected to regulated environmental conditions, including a precisely maintained temperature of 22 C, humidity levels ranging between 40% and 50%, and a strictly adhered to light/dark cycle of 12 h each, with unrestricted access to both water and food