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Ophthalmology 114 , 14161417 (2007)

In addition, previous studies have shown that ferroptosis and pyroptosis are also associated with granulosa cell death in polycystic ovarian syndrome (PCOS) and diminished ovarian reserve (DOR) ( Gpx4 ), Solute Carrier Family 7 Member 11 ( Slc7a11 ), Acyl-CoA Synthetase Long Chain Family Member 4 ( Acsl4 ), Lysophosphatidylcholine Acyltransferase 3 ( Lpcat3 ) , Apoptosis Inducing Factor Mitochondria Associated 2 ( Aifm2 ), and GTP Cyclohydrolase 1 ( Gch1 ), and the pyroptosis-related genes, including Caspase 1 ( Casp1 ), Caspase 11 ( Casp11 ) , Gasdermin D ( Gsdmd ), and Gasdermin E ( Gsdme ), were analyzed by qPCR

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5.3 Endocrine therapy resistance Endocrine therapy, a crucial method in cancer treatment, employs steroid drugs to alter the conditions necessary for tumor development, resulting in the suppression of tumor progression