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Keywords: FOXO4-DRI, Leydig cell, senescence, male late-onset hypogonadism, senolytics INTRODUCTION Male late-onset hypogonadism (LOH) is a clinical and biochemical syndrome associated with advancing age

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[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Leite G., Rezaie A., Mathur R., Barlow G.M., Rashid M., Hosseini A., Wang J., Parodi G., Villanueva-Millan M.J., Sanchez M., et al

This longevity of research interest is itself informative: compounds that fail to replicate across independent laboratories typically disappear from the literature within a decade