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It is also strongly pro-angiogenic: in rat and endothelial-cell models it promoted new blood-vessel formation and blood-flow recovery by up-regulating the VEGFR2AkteNOS pathway[2]

While full restoration to youthful levels isnt guaranteed and NAD+ therapy research in humans is still a bit limited, there are studies that support its superiority over diet and exercise alone in significantly raising NAD+ concentrations and promoting healthier aging, especially after 40 when natural production declines sharply

Most common salts of Epitalon available commercially are in combination with acetic or triuoroacetic (TFA) counterions

doi: 10.1186/s40580-021-00260-z 20 DHerdeKKryskoDV