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Any combination with supplements or medications must be assessed by a qualified healthcare professional to avoid serious risks including hypoglycaemia, gastrointestinal harm, and drug interactions

Campbell L, Howie F, Arthur JR, Nicol F, Beckett G

4 In SURMOUNT-1, considerably more tirzepatide than placebo patients experienced GI adverse events, e.g., nausea 30% vs

However, the possibility of heart palpitations as a side effect raises an important question: do these benefits outweigh the risks

The STEP 1 extension data showed approximately two-thirds of total weight loss regained within one year of discontinuation, emphasizing the chronic nature of obesity and the need for sustained treatment in most cases