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[21] In rare cases of POMC deficiency, treatment with setmelanotide, a selective melanocortin-4 receptor agonist, has been effective

331,332 Multiple PD-associated genes, such as LRRK2, SYNJ1, DNAJC6, and DNAJC13, regulate synaptic endocytosis, autophagy, lysosomal function, and endolysosomal trafficking, underscoring the intertwined regulation of vesicular dynamics and proteostasis in dopaminergic neurons

References Dweik RA, Comhair SA, Gaston B, Thunnissen FB, Farver C, et al: NO chemical events in the human airway during the immediate and late antigen-induced asthmatic response

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