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The weight loss achieved with GLP-1s indirectly improves OSA symptoms by reducing the fat deposits surrounding the upper airway that contribute to its collapse during sleep

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This modification prevents the breakdown of CJC-1295 and allows it to bind with plasma albumin, thus prolonging its half-life

When administered subcutaneously once weekly, tirzepatide binds to both GIP and GLP-1 receptors on pancreatic beta cells, enhancing glucose-dependent insulin secretion