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When they are discontinued: A1C levels often rise Fasting blood sugar may increase Diabetes symptoms may return Thus, for patients with Type 2 diabetes, stopping a GLP-1 without an alternative treatment plan can increase the risk of worsening blood sugar control, making close medical supervision and proactive adjustments essential.2 Digestion Speeds Back Up Once you discontinue a GLP-1, your digestive system returns to its baseline rhythm: Food empties from the stomach more quickly Earlier hunger cues return Cravings may become harder to control Many patients find it helpful to follow structured eating guidance like the one outlined in our nutritional support program