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Given that pharmacological alternatives only targeting specific comorbid conditions are limited, and with a significant burden of side effects, further studies utilizing complementary and alternative medicine for the treatment of ASD are justified

Research suggests that spermidine helps protect NAD+ levels from the effects of chronic inflammation

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REDD1 is a gatekeeper of murine hematopoietic stem cell functions during stress responses

These proinflammatory molecules also induce the above lesions through the nuclear factor-B (NF-B), Janus kinase/signal transducers and activators of transcription (JAK/STAT), and TGF-/Smad signaling pathways[99-101]