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Blood was collected at 0.25, 0.5, 1, 2, 4, 8, 24 and 48 h for subcutaneous and oral gavage groups

1% Triton X-100 was added, and samples rocked at 4C for 30 minutes before centrifugation and incubation of supernatants with glutathione beads (GE17-0756-01, Sigma Aldrich) for 2 hours rocking at room temperature to capture the GST-D4H*-mCherry protein

En casos graves, las lesiones cutneas pueden ser desfigurantes y el paciente puede solicitar la suspensin definitiva de la medicacin

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