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Chemical Name: L-Valine, glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl- acetate

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10.2337/dc18-2207 125 GerichJ

However, there are two major analytical challenges associated with detecting enhancing substances in DBS: (1) low concentration of these compounds and (2) high abundance of matrix interference associated with the use of DBS cards

The reductions in lean mass do not necessarily indicate pathological muscle loss, as improvements in body composition, physical function, and quality of life have been reported with semaglutide and tirzepatide in subanalyses of the STEP-1 and SURMOUNT-1 programs [7,8]