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Do not exceed the stated recommended daily intake

Txnip binds to thioredoxin, which has antioxidant activity, and inhibits its activity 43

JomovaK.ValkoM.2011Advances in metal-induced oxidative stress and human disease28365870030-0483X

Dalton Trans 47:36133637 Singh AK, Pomorski A, Wu S, Peris-Daz MD, Czepczyska-Krel H, Krel A (2023) The connection of - and -domains in mammalian metallothionein-2 differentiates Zn(II) binding affinities, affects folding, and determines zinc buffering properties

Although these studies suggest that NTS2 enhances sensitivity to higher hypnotic doses of alcohol while NTS1 increases sensitivity to lower ataxic doses of alcohol, and by these mechanisms both receptors may suppress alcohol consumption (Lee et al., 2011)