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Glutathione deficiency and oxidative stress have been implicated in the pathogenesis of neurological diseases such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis

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For example, the variant 677T is most commonly associated with cerebral vascular accident (stroke), elevated homocysteine, cardiovascular disease risk, peripheral neuropathy, deep vein thrombosis, early-onset heart disease, stillbirth, neuro-tube defect, cleft lip, and preeclampsia

It is a sign that the medication is engaging new receptors and your system is recalibrating