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The primary structural difference between PfGST and other GST structures is the presence of an additional loop in the Plasmodium enzyme, connecting the alpha helix 4 to alpha helix 5 (residues 113-120) which are known to be involved in dimer formation and consequently in enzyme activity ( Plasmodium GST and therefore, potential novel antimalarial drugs

Where applicable, reports may include additional quality parameters

Trimethylamin-N-oxid (TMAO) im Blut angereichert anstatt mit dem Urin ausgeschieden zu werden

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All children attending the clinic during the time period of the study were invited to take part