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In addition, in the xenograft model, ultra-small silica nanoparticles were shown to induce ferroptosis by increasing the transport and accumulation of iron in cells and inhibit tumor growth [206, 207]

Hal tersebut terjadi karena glutathione menekan aktivitas enzim tirosinase yang berperan dalam pembentukan melanin, sehingga kadar melanin lebih rendah dan membuat kulit tampak cerah.