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This can increase to 11.515.7% when intensive behavioral therapy, exercise and calorie restriction are added [112]

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Furthermore, pooled analyses from CANVAS and CREDENCE reinforced the kidney protection of canagliflozin in DKD, irrespective of diabetes duration [49] or body mass index [50]

The membrane was washed three times in PBS prior to 1 hour of incubation in PBS containing goat anti-mouse IgG conjugated with horseradish peroxidase