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This binding activates cAMP-dependent pathways, leading to the opening of specific potassium channels, such as ATP-sensitive potassium channels (a recently discovered trigger of migraine aura) [18, 40]

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A strong antioxidant network maintains the balance between free radical production and removal, resulting in minimal overall damage caused by free radicals

Evidence that quinolinic acid severely impairs energy metabolism through activation of NMDA receptors in striatum from developing rats

2 (download XLSX Numerical data for titration experiments Source Data Fig