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Muscle tissue contains a high density of mitochondria more than almost any other tissue in the body

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However, the same pathway affects colonic motility and may influence intestinal inflammation patterns, raising concerns in patients with pre-existing inflammatory bowel disease

It contributes to: Constipation Cramping Slower digestion What helps: Consistent water intake Electrolytes if needed Sipping throughout the day (not chugging) References: Mayo Clinic hydration guidance 7

Coordination between prescribers is essential to monitor for medication interactions and mood stability