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Patients for whom the higher magnitude of average weight loss is needed to support meaningful improvement in conditions such as sleep apnoea, severe insulin resistance, or non-alcoholic fatty liver disease

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1.5 mg): constipation (0.7%, 3.9%, 3.7%), flatulence (1.4%, 1.4%, 3.4%), abdominal distension (0.7%, 2.9%, 2.3%), gastroesophageal reflux disease (0.5%, 1.7%, 2.0%), and eructation (0.2%, 0.6%, 1.6%)