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Ferroptosis in Epilepsy Previous studies have shown that early persistent dysregulation of iron metabolism and activation of antioxidant signals are pathological features of focal cortical dysplasia type IIb (FCD IIb) and tuberous sclerosis complex (TSC) (Zimmer et al., 2020)

Ferroptosis: role of lipid peroxidation, iron and ferritinophagy

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In APOE knockout mice expressing human APOE4, enhanced measures of anxiety are associated with reduced microtubule-associated protein 2 (MAP2)-positive neuronal dendrites in the central nucleus of the amygdala (Robertson et al., 2005)