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Other processes it helps with include the following: Nerve function and wellness Cognitive function Immune system wellness Homocysteine metabolism Synthesis of DNA and RNA Vitamin B12 also plays a critical role in converting the food you eat into sustainable energy

This can be a problem for your organs, which are now not getting enough oxygen, leading to a whole host of concerning symptoms, which include: Anemia Fatigue and weakness Depression Irritability Yellowing skin Soreness of mouth and tongue Weight loss or decreased appetite Numbness of extremities Vision problems Other neurological and psychological symptoms may include fogginess, confusion, and a shift in personality and behavior

Recent Clinical Trials and Research Findings Recent studies suggest high-dose B12 can help with nerve pain

A large 2026 study found that colon cancer patients with very high B12 levels survived a median of around five years, compared with nearly eleven years for those with normal levels

Importantly, subcutaneous injections bypass the gastrointestinal tract, so absorption is generally unaffected by altered surgical anatomy